• Coronary heart disease (CHD) is responsible for over 300,000 deaths annually in the United States. An improved method for detecting CHD could have a substantial clinical impact given that sudden cardiac death is the initial presentation in 15% of patients with CHD. Building on the idea that systemic effects of CHD risk factors are a conglomeration ...

  • An improved method for detecting coronary heart disease (CHD) could have substantial clinical impact. Building on the idea that systemic effects of CHD risk factors are a conglomeration of genetic and environmental factors, we use machine learning techniques and integrate genetic, epigenetic and phenotype data from the Framingham Heart Study...